Hello netgekko. I've been on it for four months now and am approaching goal weight. To answer your question, so far I haven't seen any negatives with one exception - the social aspect of the diet is pretty awful! I suppose its hard to answer until I get to goal and then hopefully manage to keep the weight off. I am a bit worried about how difficult it might be to maintain but that seems to be a problem for anyone who loses a lot of weight.